Direct conversion of cardiac fibroblasts into induced cardiomyocytes (iCMs) by forced expression of defined factors holds great potential for regenerative medicine by offering an alternative strategy for treatment of heart disease.Successful iCM conversion can be achieved by minimally using three transcription factors, Mef2c (M), Gata4(G), and Tbx5
Study on the Frequent Expression of Rodgers and Chido, Red Blood Cell Antigens, in Iranian Healthy Population
Rodgers (Rg) and Chido (Ch) are blood-group antigens and they determine the fourthcomponentof human complement C4.Rodgers and Chido are associated with two C4isotypes (C4A and C4B).In addition to genotype determination, study on expression ofRg and Chido could be useful in disease studies.DNA was extracted from the whole blood of 60 normal individu
Angular Displacement Control for Timoshenko Beam by Optimized Traveling Wave Method
The vibration of flexible structures in spacecraft, such as large space deployable reflectors, solar panels and large antenna structure, has a great impact on the normal operation of spacecraft.Accurate vibration control is necessary, and the control of angular displacement is a difficulty of accurate control.In the traditional control method, the
Establishment of a new cell line from lepidopteran epidermis and hormonal regulation on the genes.
When an insect molts, old cuticle on the outside of the integument is shed by apolysis and a new cuticle is formed under the old one.This process is completed by the epidermal cells which are controlled by 20-hydroxyecdysone (20E) and juvenile hormone.To understand the molecular mechanisms of integument remolding Grinder and hormonal regulation on
Subversion of the Immune Response by Human Pathogenic Mycoplasmas
Mycoplasmas are a large group of prokaryotes which is believed to be originated from Gram-positive Grinder bacteria via degenerative evolution, and mainly capable of causing a wide range of human and animal infections.Although innate immunity and adaptive immunity play crucial roles in preventing mycoplasma infection, immune response that develops